March 26-28, 2020   |   University Park, PA  

PennState College of Engineering

NEBEC 2020 Invited Speakers

 

Day 1 Plenary Speaker: Professor Xiao Yun Xu
Department of Chemical Engineering
Imperial College, London
Xiao Yun Xu is a Professor of Biofluid Mechanics in the Department of Chemical Engineering at Imperial College London.  She joined Imperial College in 1998 as a Lecturer, and became a full Professor in 2009. She received her BSc and MSc degrees in Thermo-Fluids Engineering from Dalian University of Technology in China, and PhD in Mechanical Engineering from City University, London. Her research is focused on developing and using computational models to understand fluid flow and mass transfer in biological systems. She has established and led her research group to the cutting edge of multiscale and multi-physics modelling of transport processes in biological systems, with applications ranging from evaluations of endovascular interventional procedures for the treatment of aortic diseases to understanding of drug transport in solid tumours and thrombolytic therapies. She has published more than 160 peer-reviewed journal papers. She currently serves as an Associate Editor of International Journal for Numerical Methods in Biomedical Engineering, a member of the board of consulting editors for Journal of Biomechanics, and a member of the editorial board of Medicine in Novel Technology and Device. She won the 2018 Imperial College President's Medal for Excellence in Research Supervision.

 

 

 

Day 2 Plenary Speaker: Professor Song Li
Department of Bioengineering
UCLA
Dr. Song Li had his Ph.D. and postdoctoral training at UC San Diego with Professor Shu Chien. Dr. Li was a professor in bioengineering at UC Berkeley between 2001 and 2015. In 2016, he moved to UC Los Angeles as a Chancellor Professor of Bioengineering and Medicine, and he currently serves as the Chair of the Bioengineering Department.  Dr. Li's research is focused on stem cell engineering, mechanobiology and regenerative engineering. His work has contributed to the understanding of how biophysical factors regulate the vascular functions, stem cell differentiation and cell reprogramming. His laboratory also engineered biophysical factors, stem cells and functional micro/nanomaterials for tissue engineering and drug delivery. Dr. Li has been elected as a Fellow of American Institute of Medical and Biological Engineering, a Fellow of Biomedical Engineering Society, and a Fellow of the International Academy of Medical and Biological Engineering.

 

 

 

Keynote Speaker: Dr. Henry Donahue
Professor and Distinguished Chair, Department of Biomedical Engineering
Co-director VCU Institute for Engineering and Medicine
Virginia Commonwealth University
Dr. Donahue is Eminent Scholar and Alice T. and William H. Goodwin, Jr. Endowed Professor and Chair, Department of Biomedical Engineering at Virginia Commonwealth University. He received his Ph.D. in Biology from the University of California, Santa Barbara and completed a post-doctoral fellowship at the Mayo Clinic. He has nearly 30 years of experience studying musculoskeletal biology, using both in vitro and in vivo models. His research focuses on understanding the mechanism by which bone and muscle adapt to their mechanical environment; examining the effects of space flight on musculoskeletal tissues and exploiting biophysical signals, including shear stress and nanotopography, to develop innovative strategies to regenerate musculoskeletal tissue lost to disease, injury or ageing. His research has been continually funded by the National Institutes of Health for over 25 years and he has also had funding from the Department of Defense, NASA/National Space Biology Research Institute, private foundations and industry. In 2017 he received the Orthopaedic Research Society Outstanding Achievement in Mentoring Award. Dr. Donahue is a fellow of the American Institute for Medical and Biological Engineering, the American Association for the Advancement of Science and the American Society for Bone and Mineral Research.

 
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Keynote Speaker: Dr. Kevin Janes
Associate Professor, Department of Biomedical Engineering
University of Virginia
Kevin Janes received his B.S. and B.A. degrees in Biomedical Engineering and Spanish at Johns Hopkins University in 1999. He was a Fulbright Scholar at La Universidad de Santiago de Compostela in Spain before attaining his Ph.D. in Bioengineering at M.I.T. in 2005 under the joint supervision of Douglas Lauffenburger and Michael Yaffe. Dr. Janes completed a postdoctoral fellowship at Harvard Medical School in the Department of Cell Biology with Joan Brugge and began his faculty position at the University of Virginia in 2008. During that time, Dr. Janes was recognized as a Pew Scholar, a Packard Fellow, a Kavli Fellow, and a recipient of the NIH Director's New Innovator Award. He is currently an Associate Professor in the Department of Biomedical Engineering at the University of Virginia, the Chair of the Tumor Biochemistry and Endocrinology study section at the American Cancer Society, and a member of the Board of Reviewing Editors for Science Signaling.

 

 

 

Keynote Speaker: Dr. Kang Kim
Associate Professor, Medicine, Bioengineering Department, Mechanical Engineering & Materials Science
University of Pittsburgh
Kang Kim, Ph.D. is an Associate Professor of Medicine, Bioengineering, and Mechanical Engineering & Material Science at The University of Pittsburgh. Dr. Kim directs the Multi-modality Biomedical Ultrasound Imaging Laboratory at the Center for Ultrasound Molecular Imaging and Therapeutics  – home to research projects focused on basic science, pre-clinical studies and clinical translation of medical instrumentation, signal/image processing algorithms and imaging contrast/therapeutic agents.

Dr. Kim earned his Bachelor's in Educational Physics at Seoul National University in Seoul, South Korea. He then went to the University of Pierre & Marie Curie (Paris 6) in Paris, France for his Master's in Physics before he moved to the United States for his Ph.D. in Acoustics at The Pennsylvania State University. After obtaining his Ph.D., Dr. Kim became a Postdoctoral Research Fellow, then a Research Faculty in the Department of Biomedical Engineering at the University of Michigan.

Dr. Kim's research seeks to develop and translate state-of-the-art noninvasive ultrasound imaging technologies to (1) improve disease diagnosis (2) guide therapeutic strategies and (3) evaluate therapeutic efficacy. His research emphasis is on development and application of multi-modality imaging systems that are based on a fundamental understanding of how sound and light interact with soft tissues, and are capable of characterizing the structural, mechanical, compositional properties of tissues and organs and their underlying biological activities in cellular level.

 

 

 

Keynote Speaker: Dr. Catherine K. Kuo
Associate Professor
Department of Biomedical Engineering, University of Rochester
Department of Orthopaedics, University of Rochester Medical Center
Center for Musculoskeletal Research, University of Rochester Medical Center
Catherine K. Kuo is an Associate Professor in the Departments of Biomedical Engineering and Orthopaedics and in the Center for Musculoskeletal Research at the University of Rochester. Her research program is designing embryonic development-inspired mechanotherapeutic interventions to treat adult tendon injuries and diseases. She is an AIMBE Fellow and the recipient of Sweden's Go:Life Award for Innovation in Research, Stem Cell Research and Therapy Emerging Investigator Award, NSF CAREER Award, and the March of Dimes Basil O'Connor Starter Scholar Research Award. Her research has been continuously funded by the NIH, DoD, NSF, the March of Dimes Foundation, and industry. She serves on the editorial boards for Tissue Engineering (Parts A, B, C), Biomedical Materials and IEEE Open Access Journal of Engineering in Medicine and Biology; on the advisory council for the International Society of Ligaments and Tendons; and on the Orthopaedic Research Society Publications Advisory Board for the Journal of Orthopaedic Research. She received her B.S.E. in materials science and engineering and Ph.D. in biomaterials and macromolecular science and engineering from the University of Michigan and did her postdoctoral studies at the NIH in the Cartilage Biology and Orthopaedics Branch.

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Keynote Speaker: Dr. Peter Lewin
R. B. Beard Distinguished University Professor of Electrical and Computer Engineering
Drexel University
Peter A. Lewin, M.Sc., Ph.D. is R.B. Beard Distinguished University Professor of Electrical and Computer Engineering in the College of Engineering at Drexel University, Philadelphia. He is also Director of the Ultrasound Research and Education Center in The School of Bioengineering, Bioscience and Health Systems at Drexel University. Dr. Lewin obtained his M.S. degree in Electrical Engineering in 1969 and the Ph.D. in Physical Acoustics in 1979 in Copenhagen, Denmark. Before receiving his Ph.D. degree he was employed by Bruel and Kjaer, Denmark, where he was involved in the development of underwater piezoelectric transducers and associated electronics. From 1978 to 1983 he was associated with the Danish Institute of Biomedical Engineering (now Force Institutes) and The University of Denmark, Copenhagen-Lyngby, where his research activities primarily focused on propagation of ultrasound waves in inhomogeneous media and development of PVDF transducers. In 1983 he joined the faculty of Drexel University. Dr. Lewin was awarded several patents in the field of ultrasound and has authored or co-authored almost 250 scientific publications, most of them on topics in ultrasound and is co-editor of Ultrasonic Exposimetry (CRC Press, 1993), a landmark book in the field. His current interests are primarily in the field of biomedical ultrasonics including the design and testing of piezoelectric transducers and sensors, power ultrasonics, ultrasonic exposimetry, tissue characterization using nonlinear acoustics, biological effects of ultrasound, applications of shock waves in medicine and image reconstruction and processing. He advised numerous Ph.D. students; in this context it may be worthwhile to add that his most recent research results describing the outcome of clinical studies in the field of ultrasonically assisted chronic wound healing are featured on the NIH website.

 

 

 

Keynote Speaker: Dr. Brenda Ogle
Professor and Department Head, Department of Biomedical Engineering
University of Minnesota
Brenda Ogle is Professor and Head of Biomedical Engineering, Professor of Pediatrics, and Director of the Stem Cell Institute at the University of Minnesota. Her research team investigates the impact of extracellular matrix proteins on stem cell behavior especially in the context of the cardiovascular system.  Insights gleaned over the years established mechanistic links between integrin engagement and the activity of critical transcription factors and most recently led to the development of optimized, extracellular matrix-based bioinks for 3D printing of cardiac muscle mimics featured in Newsweek. The primary strength of her laboratory is the ability to span multiple subdisciplines within both basic science (i.e., stem cell biology, cell-cell fusion, and extracellular matrices) and engineering (cytometry, instrumentation, and 3D printing) fields.  Her work received funding from the National Institutes of Health, the National Science Foundation, the Department of Defense, the American Heart Association, the Coulter Foundation, Regenerative Medicine Minnesota, and MnDRIVE.  She has partnered on research projects with Becton Dickinson, iCyt and Medtronic. Professor Ogle is an elected fellow of the American Institute for Medical and Biological Engineering and a member of the Board of Directors of the Biomedical Engineering Society.  She has served as co-chair of the Women's Faculty Cabinet, UMN and is recipient of the Mullen-Spector-Truax Women's Leadership Award.   

 

 

 

Keynote Speaker: Dr. Bing Xu
Professor of Chemistry
Brandeis University
After receiving his BS and MS from Nanjing University in 1987 and 1990, Bing Xu obtained his PhD in 1996 from the University of Pennsylvania. Before starting his independent research at the Hong Kong University of Science and Technology (HKUST) in August 2000, he was an NIH postdoctoral fellow at Harvard University. He was tenured as an associate professor in January 2006 and became a full professor in July 2008 at HKUST. Bing Xu currently is a professor in the Department of Chemistry, Brandeis University. His research focuses on the applications of molecular engineering in materials, biology, and medicine.

Abstract for 2020 NEBEC Presentation - Enzymatic Noncovalent Synthesis for Biomaterials
Enzymatic reactions and noncovalent interactions are two fundamental non-genetic features of cells. Enzymatic noncovalent synthesis (ENS), a process that integrates enzymatic reactions and supramolecular (i.e., noncovalent) interactions for spatial organization of higher-order molecular assemblies, represents an emerging research area at the interface of physical (e.g., chemistry, physics, and nanotechnology) and biological sciences (e.g., structural biology, biochemistry, and cell biology). This talk will focus on the biological functions of ENS of small molecules, mainly short peptides. For example, pericellular and/or intracellular ENS selectively inhibits cancer cells and tumor growth; subcellular ENS delivers drugs and transfects gene expression into mitochondria; intercellular ENS enables cell morphogenesis (i.e., a 2D cell sheet become 3D cell spheroids). These studies have illustrated the use of supramolecular processes to control cellular functions for biology and medicine.

 

 

 

Keynote Speaker: Dr. Yihong Yang
Chief, Magnetic Resonance Imaging and Spectroscopy
National Institutes of Health
Dr. Yihong Yang is a Senior Investigator of the National Institutes of Health (NIH) and Chief of the Magnetic Resonance Imaging and Spectroscopy Section at the National Institute on Drug Abuse (NIDA). He has made significant contributions to the field of MRI methodology and its applications to neurological and psychiatric disorders, and has published over 190 original research papers and contributed several book chapters. He was elected as a Fellow of the International Society for Magnetic Resonance Imaging in Medicine (ISMRM) in 2017 and Fellow of the American Institute for Medical and Biological Engineering (AIMBE) in 2018.

 

 

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